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doi: 10.1001/jama.2015.1346 2 S

Increases endogenous IGF-1, supports thermogenesis, and promotes lean muscle

When human cells are integrated into microfluidic platforms that mimic key physiological parameters, including oxygen gradients, fluid flow, and multicellular tissue interactions, these systems provide improved translational relevance than conventional models [175, 176]

Researchers regularly explore this axis to better understand how growth-related signals integrate with metabolism, tissue maintenance, and cellular communication